HitPredict

Interactor 1: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Interactor 2: RFXK (Q9Z205)
DNA-binding protein RFXANK (Ankyrin repeat-containing adapter protein Tvl-1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: Rfxank

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16236793
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1076 Mm			1 269
+	Hs
		149843 HDAC4_HUMAN (1-1064): 0: 808: 93.38		RFXK_HUMAN (1-269): 1.29e-72: 224: 80.74
+	Hs
		880823 HDAC4_HUMAN (1-1064): 0: 808: 93.38		ANRA2_HUMAN (64-261): 4.11e-71: 222: 62.12
+	Mm
		1157667 HDAC4_MOUSE (1-1065): 0: 837: 100.00		TNKS1_MOUSE (15-139): 6.44e-21: 94.1: 10.94
+	Mm
		1112794 Q3UJF1_MOUSE (2-1076): 0: 649: 54.47		RFXK_MOUSE (1-269): 2.22e-81: 247: 100.00
+	Hs
		149935 HDAC9_HUMAN (25-1017): 0: 666: 55.86		RFXK_HUMAN (1-269): 1.29e-72: 224: 80.74
+	Hs
		1334238 HDAC9_HUMAN (25-1017): 0: 666: 55.86		ANRA2_HUMAN (64-261): 4.11e-71: 222: 62.12
+	Hs
		149938 HDAC5_HUMAN (1-1076): 0: 658: 54.49		RFXK_HUMAN (1-269): 1.29e-72: 224: 80.74
+	Hs
		1334240 HDAC5_HUMAN (1-1076): 0: 658: 54.49		ANRA2_HUMAN (64-261): 4.11e-71: 222: 62.12
+	Mm
		1112781 Q3UJF1_MOUSE (2-1076): 0: 649: 54.47		ANRA2_MOUSE (64-261): 4.21e-69: 217: 61.62
+	Hs
		149897 HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84		RFXK_HUMAN (1-269): 1.29e-72: 224: 80.74
+	Hs
		177384 HDAC3_HUMAN (647-1073): 3.57e-153: 464: 20.77		ANRA2_HUMAN (64-261): 4.11e-71: 222: 62.12
+	Hs
		257609 HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03		ANR17_HUMAN (4-155): 1.31e-32: 128: 14.84
+	Hs
		257678 HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84		ANR17_HUMAN (4-155): 1.31e-32: 128: 14.84
+	Hs
		1219802 HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84		ANKH1_HUMAN (3-122): 1.84e-21: 95.6: 9.84
+	Hs
		166921 HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03		ANR28_HUMAN (2-154): 1.19e-19: 90.2: 11.95
+	Hs
		1038721 HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03		EHMT1_HUMAN (5-147): 6.82e-17: 82.2: 13.17
+	Hs
		1270450 HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84		EHMT1_HUMAN (5-147): 6.82e-17: 82.2: 13.17
+	Hs
		1038631 HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03		EHMT2_HUMAN (121-238): 8.96e-13: 70.1: 35.59
+	Hs
		1270381 HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84		EHMT2_HUMAN (121-238): 8.96e-13: 70.1: 35.59