HitPredict

Interactor 1: M9PGI6 (M9PGI6)
Secretory 22, isoform B
Gene: Sec22

Interactor 2: STX5 (Q24509)
Syntaxin-5 (Sed5 protein) (dSed5)
Gene: Syx5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25670863, 22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005783 - endoplasmic reticulum GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006906 - vesicle fusion and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Dm			1 467
+	Rn
		996534 SC22B_RAT (1-213): 7.33e-81: 241: 56.22		STX5_RAT (123-450): 1.25e-84: 265: 51.22
+	Hs
		263229 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX5_HUMAN (123-450): 1.28e-73: 237: 50.92
+	Dm
		115805 M9PGI6_DROME (1-213): 2.29e-85: 253: 100.00		STX1A_DROME (160-467): 3e-64: 211: 14.56
+	Mm
		139056 SC22B_MOUSE (1-213): 7.33e-81: 241: 56.22		STX1A_MOUSE (161-463): 4.48e-68: 220: 16.50
+	Hs
		263248 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX1A_HUMAN (161-463): 1.88e-67: 219: 16.17
+	Hs
		263179 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX2_HUMAN (161-466): 1.53e-65: 214: 15.36
+	Dm
		115838 M9PGI6_DROME (1-213): 2.29e-85: 253: 100.00		Q9VR90_DROME (160-460): 9.92e-52: 180: 14.80
+	Hs
		263226 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX4_HUMAN (161-466): 5.37e-57: 192: 17.74
+	Hs
		263279 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX12_HUMAN (196-454): 2.65e-50: 174: 16.60
+	Dm
		115841 M9PGI6_DROME (1-213): 2.29e-85: 253: 100.00		Q9VU45_DROME (234-463): 4.64e-44: 158: 15.88
+	At
		249598 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP41_ARATH (158-466): 2.04e-53: 183: 15.71
+	At
		1352876 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP43_ARATH (158-466): 1.08e-51: 179: 15.08
+	At
		1352985 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP42_ARATH (169-466): 7.49e-52: 179: 14.75
+	At
		812689 VA722_ARATH (34-200): 8.86e-71: 216: 22.22		SY111_ARATH (158-449): 9.15e-49: 171: 13.09
+	At
		1114744 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SY111_ARATH (158-449): 9.15e-49: 171: 13.09
+	Hs
		178331 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX7_HUMAN (205-466): 3.46e-38: 141: 17.94
+	At
		812702 VA722_ARATH (34-200): 8.86e-71: 216: 22.22		SY121_ARATH (182-449): 2.33e-46: 165: 13.31
+	At
		1378372 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SY121_ARATH (182-449): 2.33e-46: 165: 13.31
+	At
		955702 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP22_ARATH (201-454): 3.29e-31: 122: 13.95
+	At
		955681 VA713_ARATH (33-213): 2.67e-65: 202: 23.91		SYP22_ARATH (201-454): 3.29e-31: 122: 13.95