Interactor 1: SLX4 (Q6P1D7)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: MUS81 (Q91ZJ0)
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
Gene: MUS81

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 21240276
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0046872 - metal ion binding
GO:0048476 - Holliday junction resolvase complex
GO:0072429 - response to intra-S DNA damage checkpoint signaling
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1565
Mm

1 551
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024