HitPredict

Interactor 1: KDM2B (Q6P1G2)
Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B)
Gene: KDM2B

Interactor 2: PCGF1 (Q8R023)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17296600, 23395003
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1309 Mm			1 259
+	Hs
		1245590 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		PCGF1_HUMAN (1-259): 3e-84: 253: 98.07
+	Mm
		639474 KDM2B_MOUSE (1-1309): 0: 1305: 100.00		BMI1_MOUSE (30-255): 3.93e-67: 212: 36.17
+	Hs
		718034 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		BMI1_HUMAN (30-255): 5.38e-68: 214: 35.87
+	Hs
		718413 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		PCGF2_HUMAN (30-255): 1.06e-62: 201: 36.40
+	Hs
		1108521 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		PCGF3_HUMAN (32-255): 1.5e-59: 190: 39.42
+	Mm
		1158239 KDM2B_MOUSE (1-1309): 0: 1305: 100.00		RING2_MOUSE (24-259): 1.52e-46: 160: 15.34
+	Hs
		1245594 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		PCGF6_HUMAN (26-252): 2.08e-49: 167: 35.50
+	Hs
		1245587 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		RING2_HUMAN (24-259): 2.14e-46: 159: 15.34
+	Hs
		1197574 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		PCGF5_HUMAN (30-255): 1.06e-45: 155: 28.85
+	Mm
		193408 KDM2B_MOUSE (1-1309): 0: 1305: 100.00		RING1_MOUSE (24-153): 8.05e-34: 128: 21.64
+	Hs
		987996 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		RING1_HUMAN (24-153): 5.38e-33: 125: 21.64
+	Dm
		627171 JHD1_DROME (9-1296): 0: 810: 28.06		SUZ2_DROME (13-254): 6.01e-53: 186: 26.61
+	Dm
		728809 JHD1_DROME (9-1296): 0: 810: 28.06		PSC_DROME (26-256): 2.99e-52: 184: 28.22
+	Dm
		1367224 JHD1_DROME (9-1296): 0: 810: 28.06		Q9VV77_DROME (32-257): 1.47e-56: 182: 38.43
+	Dm
		1361711 JHD1_DROME (9-1296): 0: 810: 28.06		RING1_DROME (24-153): 5.38e-32: 123: 24.63
+	Hs
		718320 PHF8_HUMAN (14-481): 7.06e-158: 504: 33.26		BMI1_HUMAN (30-255): 5.38e-68: 214: 35.87
+	Hs
		1019385 PHF8_HUMAN (14-481): 7.06e-158: 504: 33.26		TRI26_HUMAN (32-223): 5.64e-29: 116: 19.90
+	Hs
		1311563 KDM2A_HUMAN (818-1309): 5.68e-64: 240: 42.02		PCGF1_HUMAN (1-259): 3e-84: 253: 98.07
+	Hs
		536886 FXL19_HUMAN (551-1309): 1.32e-105: 352: 41.32		TRI27_HUMAN (32-225): 3.7e-35: 133: 14.43
+	Hs
		717733 KMT2A_HUMAN (344-837): 2.1e-55: 215: 13.71		BMI1_HUMAN (30-255): 5.38e-68: 214: 35.87