HitPredict

Interactor 1: KDM2B (Q6P1G2)
Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B)
Gene: KDM2B

Interactor 2: SKP1 (Q9WTX5)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
Gene: SKP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	17296600
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1309 Mm			1 163
+	Hs
		928997 KDM2B_HUMAN (12-1309): 0: 1287: 94.38		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Dm
		285018 JHD1_DROME (9-1296): 0: 810: 28.06		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Hs
		928952 FXL19_HUMAN (551-1309): 1.32e-105: 352: 41.32		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929126 KDM2A_HUMAN (818-1309): 5.68e-64: 240: 42.02		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929008 FBX41_HUMAN (716-1271): 7.57e-52: 200: 14.87		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Mm
		1376704 SKP2_MOUSE (923-1306): 1.3e-52: 193: 18.48		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	Hs
		928895 SKP2_HUMAN (923-1306): 6.26e-51: 188: 17.26		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929111 FBXL2_HUMAN (1018-1293): 1.2e-50: 187: 20.34		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Mm
		1321913 FXL20_MOUSE (1032-1291): 2.04e-49: 184: 21.15		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	Hs
		929033 FXL20_HUMAN (1032-1291): 2.04e-49: 184: 21.15		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Dm
		284987 Q7YZ95_DROME (913-1309): 1.23e-50: 190: 22.17		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Hs
		928983 FXL14_HUMAN (1050-1282): 1.95e-37: 148: 17.90		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929099 FBXL7_HUMAN (845-1267): 3e-32: 134: 13.02		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	At
		1107642 Q9FMW7_ARATH (1063-1308): 1.16e-41: 160: 18.05		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1323347 Q9FMW7_ARATH (1063-1308): 1.16e-41: 160: 18.05		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		1107595 EBF2_ARATH (1050-1291): 1.44e-30: 131: 16.85		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1173681 EBF2_ARATH (1050-1291): 1.44e-30: 131: 16.85		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		221646 EBF2_ARATH (1050-1291): 1.44e-30: 131: 16.85		ASK11_ARATH (4-162): 3.36e-71: 213: 55.35
+	At
		249956 EBF2_ARATH (1050-1291): 1.44e-30: 131: 16.85		ASK12_ARATH (4-162): 7.7e-70: 209: 54.09
+	At
		286188 EBF2_ARATH (1050-1291): 1.44e-30: 131: 16.85		ASK14_ARATH (3-162): 3.46e-63: 192: 48.45