Interactor 1: CDC73 (Q6P1J9)
Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Gene: CDC73
Interactor 2: PAF1 (Q8N7H5)
RNA polymerase II-associated factor 1 homolog (hPAF1) (Pancreatic differentiation protein 2)
Gene: PAF1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 18469135, 20178742, 20305087, 21726809, 26186194, 26496610, 27462432, 28514442, 24981860, 15632063, 19136632, 29774127, 15923622, 19410543, 16024656 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC73_N~Paf1 |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000993 - RNA polymerase II complex binding GO:0001711 - endodermal cell fate commitment GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II and 8 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
