HitPredict

Interactor 1: C2D1A (Q6P1N0)
Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N)
Gene: CC2D1A

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	26496610, 31586073, 35271311, 16730941
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 951 Hs			1 224
+	Hs
		1158636 C2D1A_HUMAN (1-951): 0: 718: 100.00		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1158643 C2D1A_HUMAN (1-951): 0: 718: 100.00		CHM4A_HUMAN (1-220): 2.41e-43: 147: 56.95
+	Hs
		1132384 C2D1B_HUMAN (4-811): 2.83e-153: 476: 42.99		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Dm
		1249816 C2D1_DROME (1-810): 2.8e-143: 448: 31.66		CHM4_DROME (1-222): 3.22e-45: 151: 56.28
+	Hs
		1264782 TITIN_HUMAN (41-600): 9.36e-09: 62: 9.44		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78