HitPredict

Interactor 1: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Interactor 2: PPIL3 (Q9H2H8)
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (Cyclophilin J) (CyPJ) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3)
Gene: PPIL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PRO8NT~Pro_isomerase
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2335 Hs			1 161
+	Hs
		1159227 PRP8_HUMAN (1-2335): 0: 4632: 100.00		PPWD1_HUMAN (2-155): 9.54e-77: 241: 53.25
+	Hs
		1032296 PRP8_HUMAN (1-2335): 0: 4632: 100.00		PPIL2_HUMAN (3-161): 1e-74: 233: 49.69
+	Hs
		1159354 PRP8_HUMAN (1-2335): 0: 4632: 100.00		PPIL1_HUMAN (2-152): 4.41e-77: 228: 48.34
+	Hs
		614356 PRP8_HUMAN (1-2335): 0: 4632: 100.00		PPIB_HUMAN (6-160): 4.07e-73: 220: 45.34
+	Hs
		203530 PRP8_HUMAN (1-2335): 0: 4632: 100.00		PPIH_HUMAN (2-155): 3.04e-72: 216: 41.46
+	At
		1352311 PRP8A_ARATH (35-2335): 0: 4497: 83.58		CP18B_ARATH (3-156): 2.33e-76: 226: 50.00