Interactor 1: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Interactor 2: LSM7 (Q9UK45)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~PRP8_domainIV
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0017070 - U6 snRNA binding
GO:0046540 - U4/U6 x U5 tri-snRNP complex
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2335
Hs

1 103
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024