HitPredict

Interactor 1: FBX42 (Q6P3S6)
F-box only protein 42 (Just one F-box and Kelch domain-containing protein)
Gene: FBXO42

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 717 Hs			1 1164
+	Hs
		1267575 KLH20_HUMAN (245-560): 6.82e-22: 102: 11.78		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		254491 FBX42_HUMAN (1-717): 0: 603: 100.00		ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27
+	Hs
		551745 FBX42_HUMAN (1-717): 0: 603: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		1035180 FBX42_HUMAN (1-717): 0: 603: 100.00		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		969595 FBX42_HUMAN (1-717): 0: 603: 100.00		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Hs
		1203648 KLH20_HUMAN (245-560): 6.82e-22: 102: 11.78		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Hs
		1051524 KLH20_HUMAN (245-560): 6.82e-22: 102: 11.78		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		522559 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH1_HUMAN (393-967): 5.76e-21: 102: 11.23
+	Hs
		528383 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH6_HUMAN (623-1102): 9.65e-21: 101: 14.55
+	Hs
		1235475 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22
+	Hs
		522627 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		528416 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73
+	Hs
		1235465 LZTR1_HUMAN (25-446): 3.42e-53: 199: 15.45		MYH13_HUMAN (628-994): 2.22e-10: 67.5: 20.45
+	Hs
		522613 KEAP1_HUMAN (4-181): 1.55e-32: 135: 12.92		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		522651 KLHL9_HUMAN (243-522): 3.14e-31: 131: 10.67		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		725094 NS1BP_HUMAN (274-539): 1.03e-23: 108: 10.43		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148556 HCFC1_HUMAN (8-265): 3.09e-22: 105: 13.99		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		528428 KLHL9_HUMAN (243-522): 3.14e-31: 131: 10.67		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73