HitPredict

Interactor 1: RHGBA (Q6P4F7)
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)
Gene: ARHGAP11A

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1023 Hs			1 639
+	Hs
		1089312 RHG44_HUMAN (4-592): 3.63e-83: 289: 17.63		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		1148393 RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		1191674 SRGP1_HUMAN (5-582): 1.8e-82: 292: 16.75		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1089305 RHG44_HUMAN (4-592): 3.63e-83: 289: 17.63		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1148382 RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1066027 RHG44_HUMAN (4-592): 3.63e-83: 289: 17.63		ARHG6_HUMAN (52-634): 3.49e-68: 239: 13.68
+	Hs
		64627 RHG32_HUMAN (3-633): 1.03e-73: 269: 14.92		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Hs
		200200 SRGP3_HUMAN (5-565): 3.72e-86: 302: 16.55		SRGP2_HUMAN (2-443): 3.56e-43: 169: 11.52
+	Hs
		253374 SRGP1_HUMAN (5-582): 1.8e-82: 292: 16.75		SRGP2_HUMAN (2-443): 3.56e-43: 169: 11.52
+	Hs
		200212 SRGP3_HUMAN (5-565): 3.72e-86: 302: 16.55		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		253290 SRGP2_HUMAN (57-638): 1.38e-71: 260: 18.30		SRGP2_HUMAN (2-443): 3.56e-43: 169: 11.52
+	Hs
		64687 RHG32_HUMAN (3-633): 1.03e-73: 269: 14.92		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924636 RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		1049716 SRGP1_HUMAN (5-582): 1.8e-82: 292: 16.75		ARHG7_HUMAN (176-378): 4.79e-13: 74.6: 20.87
+	Hs
		64651 RHG32_HUMAN (3-633): 1.03e-73: 269: 14.92		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		253384 SRGP2_HUMAN (57-638): 1.38e-71: 260: 18.30		SH3R3_HUMAN (5-625): 1.58e-17: 88.8: 13.36
+	Dm
		1368053 RHGF_DROME (20-569): 1.06e-77: 277: 16.49		Q9VIN1_DROME (269-357): 7e-12: 70.7: 25.28
+	Hs
		1148372 RHG17_HUMAN (4-634): 3.06e-72: 259: 15.76		DNMBP_HUMAN (113-602): 4.85e-17: 87.7: 15.23
+	Hs
		253421 SRGP2_HUMAN (57-638): 1.38e-71: 260: 18.30		ITSN2_HUMAN (1-63): 2.7e-12: 72.2: 34.92