HitPredict

Interactor 1: CNNM4 (Q6P4Q7)
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)
Gene: CNNM4

Interactor 2: TP4A1 (Q93096)
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Gene: PTP4A1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CBS~DSPc
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 775 Hs			1 173
+	Hs
		1021801 CNNM4_HUMAN (14-775): 0: 979: 100.00		TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65
+	Hs
		1274603 CNNM2_HUMAN (15-771): 0: 886: 58.90		TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00
+	Hs
		1021825 CNNM2_HUMAN (15-771): 0: 886: 58.90		TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65
+	Hs
		1274604 CNNM1_HUMAN (46-765): 0: 728: 45.12		TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00
+	Hs
		1021828 CNNM1_HUMAN (46-765): 0: 728: 45.12		TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65
+	Dm
		2649 UEX_DROME (46-770): 0: 729: 43.89		PRL1_DROME (6-173): 4.85e-49: 158: 57.74
+	Hs
		1242821 CNNM3_HUMAN (203-771): 0: 552: 48.53		TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00
+	Hs
		260582 CNNM3_HUMAN (203-771): 0: 552: 48.53		TP4A3_HUMAN (1-172): 3.23e-57: 178: 79.07
+	Hs
		1021810 CNNM3_HUMAN (203-771): 0: 552: 48.53		TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65
+	Hs
		1144582 CNNM3_HUMAN (203-771): 0: 552: 48.53		TENS2_HUMAN (4-168): 1.8e-42: 152: 12.09