HitPredict

Interactor 1: XPO1 (Q6P5F9)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1071 Mm			1 441
+	Hs
		162254 XPO1_HUMAN (1-1071): 0: 993: 98.04		TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39
+	Hs
		163237 XPO1_HUMAN (1-1071): 0: 993: 98.04		TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40
+	Hs
		163094 XPO1_HUMAN (1-1071): 0: 993: 98.04		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		163123 XPO1_HUMAN (1-1071): 0: 993: 98.04		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Xl
		1150112 Q6NS03_XENLA (1-1071): 0: 981: 97.11		Q6DCY8_XENLA (278-439): 1.69e-23: 102: 13.42
+	Xl
		1155663 Q6NS03_XENLA (1-1071): 0: 981: 97.11		TB1RA_XENLA (279-439): 2.07e-18: 89.2: 14.11
+	Hs
		162576 XPO1_HUMAN (1-1071): 0: 993: 98.04		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		162220 XPO1_HUMAN (1-1071): 0: 993: 98.04		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Mm
		1206342 TNPO1_MOUSE (33-1045): 6.12e-138: 440: 13.63		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265469 XPOT_MOUSE (29-1023): 9.84e-111: 369: 14.74		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265559 XPO7_MOUSE (23-1013): 8.34e-106: 358: 13.27		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265394 XPO5_MOUSE (26-665): 1.76e-102: 351: 17.91		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1158890 TNPO3_MOUSE (25-901): 6.2e-82: 288: 13.12		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		207976 XPOT_HUMAN (29-1023): 4.62e-111: 370: 14.66		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Mm
		1257558 XPO7_MOUSE (23-1013): 8.34e-106: 358: 13.27		THOC3_MOUSE (148-434): 4.92e-16: 80.9: 19.03
+	Mm
		903678 XPO7_MOUSE (23-1013): 8.34e-106: 358: 13.27		WDR5_MOUSE (335-440): 3.22e-14: 75.3: 15.09