Interactor 1: CTR9 (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)
Gene: CTR9

Interactor 2: PAF1 (Q8N7H5)
RNA polymerase II-associated factor 1 homolog (hPAF1) (Pancreatic differentiation protein 2)
Gene: PAF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 30228257, 33961781, 18469135, 20178742, 20305087, 21726809, 26496610, 26902284, 24981860, 19410543, 16024656
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Paf1~TPR_19, Paf1~TPR_8
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0001711 - endodermal cell fate commitment
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1173
Hs

1 531
+ Mm
+ Dr
+ Dm
+ Hs
+ Sp
+ Sc

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Last updated: 15 Jul 2024