HitPredict

Interactor 1: CTR9 (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)
Gene: CTR9

Interactor 2: LEO1 (Q8WVC0)
RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein)
Gene: LEO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

The method score is based on:

Property	Details
Experiments	26496610, 27173435, 24981860, 15632063, 18469135, 20305087, 20178742, 22532828, 16024656
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001711 - endodermal cell fate commitment GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0016055 - Wnt signaling pathway GO:0016593 - Cdc73/Paf1 complex and 3 others more... GO:0019827 - stem cell population maintenance GO:0045638 - negative regulation of myeloid cell differentiation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	1173
Hs

1	666

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024