HitPredict

Interactor 1: SRSF1 (Q6PDM2)
Serine/arginine-rich splicing factor 1 (ASF/SF2) (Pre-mRNA-splicing factor SRp30a) (Splicing factor, arginine/serine-rich 1)
Gene: SRSF1

Interactor 2: AIRE (Q9Z0E3)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)
Gene: AIRE

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20085707
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Mm			1 552
+	Mm
		665773 PABP1_MOUSE (8-203): 8.27e-38: 141: 16.67		AIRE_MOUSE (1-552): 2.26e-142: 424: 100.00
+	Hs
		217471 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		217429 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		1018454 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		1018455 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		975239 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		KMT2A_HUMAN (101-552): 8.12e-36: 145: 12.24
+	Hs
		992741 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		975240 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		KMT2A_HUMAN (101-552): 8.12e-36: 145: 12.24
+	Dm
		332738 SRR55_DROME (17-183): 2.57e-52: 175: 39.79		CHDM_DROME (48-437): 1.75e-39: 156: 11.57
+	Hs
		975231 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		KMT2A_HUMAN (101-552): 8.12e-36: 145: 12.24
+	Hs
		1028548 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		516483 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		1028656 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		1028915 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		992774 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		331802 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35
+	Hs
		331803 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35
+	Hs
		516522 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		516595 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		KMT2C_HUMAN (285-552): 1.18e-23: 108: 14.59
+	Hs
		331795 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35