HitPredict

Interactor 1: CHD4 (Q6PDQ2)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12)
Gene: CHD4

Interactor 2: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~Chromo, Chromo~PHD, Chromo~SNF2-rel_dom
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1915 Mm			1 183
+	Hs
		1027001 CHD4_HUMAN (1-1915): 0: 1677: 97.56		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		949943 CHD4_MOUSE (1-1903): 0: 1684: 100.00		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		800380 CHD4_HUMAN (1-1915): 0: 1677: 97.56		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949784 CHD4_HUMAN (1-1915): 0: 1677: 97.56		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		203687 CHD4_HUMAN (1-1915): 0: 1677: 97.56		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		1027145 CHD5_HUMAN (79-1912): 0: 1590: 70.69		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1018451 CHD3_HUMAN (19-1908): 0: 1578: 67.88		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800360 CHD3_HUMAN (19-1908): 0: 1578: 67.88		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949764 CHD3_HUMAN (19-1908): 0: 1578: 67.88		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		123245 CHD3_HUMAN (19-1908): 0: 1578: 67.88		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		1027277 CHD8_HUMAN (66-1734): 0: 836: 23.06		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027300 CHD7_HUMAN (4-1734): 0: 822: 21.77		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		658667 SMCA1_HUMAN (609-1605): 0: 783: 27.55		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027026 CHD9_HUMAN (140-1697): 0: 782: 23.69		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		229384 SMCA5_HUMAN (567-1579): 0: 782: 26.38		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		658650 SMCA1_HUMAN (609-1605): 0: 783: 27.55		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		151406 CHD1_HUMAN (526-1758): 0: 731: 28.76		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		123332 CHD7_HUMAN (4-1734): 0: 822: 21.77		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		800446 CHD1L_HUMAN (715-1225): 4.83e-118: 399: 44.04		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949832 CHD1L_HUMAN (715-1225): 4.83e-118: 399: 44.04		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33