HitPredict

Interactor 1: Q6PED7 (Q6PED7)
Auts2 protein
Gene: Auts2

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	25519132, 34637754
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 626 Mm			1 336
+	Mm
		397 AUTS2_MOUSE (1-626): 0: 971: 100.00		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		1264228 AUTS2_HUMAN (1-626): 0: 895: 91.53		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Mm
		193409 Q6PED7_MOUSE (1-626): 0: 970: 100.00		RING1_MOUSE (10-336): 8.61e-69: 222: 52.00
+	Mm
		393 AUTS2_MOUSE (1-626): 0: 971: 100.00		PCGF3_MOUSE (36-334): 7.07e-43: 150: 16.50
+	Mm
		1161097 Q6PED7_MOUSE (1-626): 0: 970: 100.00		PCGF3_MOUSE (36-334): 7.07e-43: 150: 16.50
+	Mm
		1112807 Q6PED7_MOUSE (1-626): 0: 970: 100.00		PCGF5_MOUSE (34-334): 1.42e-40: 144: 17.59
+	Hs
		987999 AUTS2_HUMAN (1-626): 0: 895: 91.53		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		1264229 AUTS2_HUMAN (1-626): 0: 895: 91.53		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Hs
		1108524 AUTS2_HUMAN (1-626): 0: 895: 91.53		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		1197576 AUTS2_HUMAN (1-626): 0: 895: 91.53		PCGF5_HUMAN (34-334): 2.53e-39: 141: 18.24
+	Hs
		111280 J3KNZ9_HUMAN (1-224): 3.13e-80: 275: 43.36		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		1304115 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		988023 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		988026 FBSL_HUMAN (8-626): 2.14e-73: 256: 33.44		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		1316704 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Hs
		1108544 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		718208 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		718429 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		PCGF2_HUMAN (34-332): 3.57e-40: 145: 15.51
+	Hs
		1197591 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		PCGF5_HUMAN (34-334): 2.53e-39: 141: 18.24
+	Hs
		1311545 FBRS_HUMAN (1-224): 4.82e-81: 265: 43.36		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56