HitPredict

Interactor 1: SMCA1 (Q6PGB8)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (DNA-dependent ATPase SNF2L) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: Smarca1

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031491 - nucleosome binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1046 Mm			1 441
+	Hs
		267906 SMCA1_HUMAN (1-1046): 0: 1037: 94.62		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265290 SMCA5_MOUSE (61-1041): 0: 1002: 82.88		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		229258 SMCA5_HUMAN (44-1041): 0: 999: 81.76		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		658714 SMCA1_HUMAN (1-1046): 0: 1037: 94.62		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		658715 SMCA1_HUMAN (1-1046): 0: 1037: 94.62		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Mm
		57194 CHD7_MOUSE (2-1038): 0: 792: 26.71		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268053 CHD3_HUMAN (60-946): 0: 754: 29.15		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268093 CHD4_HUMAN (9-946): 0: 739: 27.60		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1161077 CHD4_MOUSE (9-946): 0: 737: 27.60		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		151466 CHD2_HUMAN (7-1044): 0: 715: 29.10		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1254435 CHD6_HUMAN (3-1031): 0: 744: 26.67		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1059779 CHD4_HUMAN (9-946): 0: 739: 27.60		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1018633 CHD3_HUMAN (60-946): 0: 754: 29.15		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1018714 CHD3_HUMAN (60-946): 0: 754: 29.15		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		1309165 CHD8_HUMAN (2-1040): 0: 750: 25.98		TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33
+	Hs
		903535 CHD8_HUMAN (2-1040): 0: 750: 25.98		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1336307 CHD8_HUMAN (2-1040): 0: 750: 25.98		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		197011 CHD3_HUMAN (60-946): 0: 754: 29.15		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		903234 CHD4_HUMAN (9-946): 0: 739: 27.60		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		197020 CHD4_HUMAN (9-946): 0: 739: 27.60		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51