HitPredict

Interactor 1: LIRA6 (Q6PI73)
Leukocyte immunoglobulin-like receptor subfamily A member 6 (Immunoglobulin-like transcript 8) (ILT-8) (Leukocyte Ig-like receptor)
Gene: LILRA6

Interactor 2: U5XH19 (U5XH19)
LILRA6
Gene: LILRA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ig~ig, Ig_2~ig, Ig_2~Ig_2
Common GO terms	GO:0005886 - plasma membrane GO:0019221 - cytokine-mediated signaling pathway GO:0032396 - inhibitory MHC class I receptor activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 481 Hs			1 481
+	Hs
		252781 LIRA6_HUMAN (1-481): 1.23e-124: 373: 100.00		LIRB3_HUMAN (1-456): 1.42e-105: 329: 91.45
+	Hs
		87574 U5XH19_HUMAN (1-481): 2.91e-122: 367: 96.88		C9JWL8_HUMAN (1-456): 1.52e-106: 331: 90.13
+	Hs
		1232785 LIRB2_HUMAN (1-447): 2.07e-100: 314: 67.34		LIRB4_HUMAN (118-338): 2.33e-41: 155: 33.78
+	Hs
		1235888 U5XH19_HUMAN (1-481): 2.91e-122: 367: 96.88		LIRA3_HUMAN (211-446): 7.21e-23: 102: 30.80
+	Dm
		1372236 Q9VPZ7_DROME (11-463): 2.19e-63: 225: 11.16		Q9VPZ7_DROME (11-463): 8.04e-60: 214: 10.52
+	Dm
		1325660 Q9GPP6_DROME (11-463): 2.41e-63: 224: 11.16		Q9GPP6_DROME (11-463): 9.54e-60: 214: 10.52
+	Hs
		252771 LIRA1_HUMAN (1-474): 8.93e-103: 317: 67.21		LIRA3_HUMAN (211-446): 7.21e-23: 102: 30.80
+	Hs
		1232784 LIRB2_HUMAN (1-447): 2.07e-100: 314: 67.34		LIRA3_HUMAN (211-446): 7.21e-23: 102: 30.80
+	Ce
		103933 SAX3_CAEEL (20-449): 8.95e-56: 202: 13.02		SAX3_CAEEL (21-470): 1.37e-57: 208: 13.29
+	Hs
		798235 KI3L1_HUMAN (1-333): 1.26e-66: 222: 35.21		KI3S1_HUMAN (1-333): 5.04e-51: 179: 34.32
+	Hs
		798163 KI3L1_HUMAN (1-333): 1.26e-66: 222: 35.21		KI2L2_HUMAN (119-340): 2.24e-49: 174: 36.77
+	Hs
		798168 KI3S1_HUMAN (1-333): 6.59e-66: 218: 34.32		KI2L2_HUMAN (119-340): 2.24e-49: 174: 36.77
+	Hs
		798136 KI3L1_HUMAN (1-333): 1.26e-66: 222: 35.21		KI2L1_HUMAN (119-340): 3.47e-47: 168: 35.87
+	Hs
		798180 KI2L3_HUMAN (119-340): 1.31e-50: 177: 37.22		KI2L3_HUMAN (119-340): 1.63e-51: 179: 37.67
+	Hs
		798230 KI3L1_HUMAN (1-333): 1.26e-66: 222: 35.21		KI2S2_HUMAN (318-445): 3.81e-17: 83.7: 35.16
+	Hs
		798265 KI2LA_HUMAN (119-319): 7.66e-53: 184: 39.11		KI2S2_HUMAN (318-445): 3.81e-17: 83.7: 35.16
+	Dm
		219801 O44924_DROME (28-414): 9.53e-47: 176: 12.94		O44924_DROME (317-474): 1.2e-12: 72.6: 14.82