HitPredict

Interactor 1: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Interactor 2: TESK2 (Q96S53)
Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2)
Gene: TESK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 571
+	Hs
		438454 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TESK2_HUMAN (1-571): 5.03e-163: 478: 100.00
+	Hs
		432182 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TESK2_HUMAN (1-571): 5.03e-163: 478: 100.00
+	Hs
		438195 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TESK1_HUMAN (41-558): 1.25e-125: 384: 47.62
+	Hs
		431880 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TESK1_HUMAN (41-558): 1.25e-125: 384: 47.62
+	Hs
		438028 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		EPHB1_HUMAN (4-371): 2.31e-115: 367: 23.76
+	Hs
		1123435 H90B4_HUMAN (25-328): 1.55e-133: 392: 83.22		TESK2_HUMAN (1-571): 5.03e-163: 478: 100.00
+	Hs
		431691 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		EPHB1_HUMAN (4-371): 2.31e-115: 367: 23.76
+	Hs
		438114 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		MERTK_HUMAN (61-437): 2.75e-100: 327: 25.00
+	Hs
		431788 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		MERTK_HUMAN (61-437): 2.75e-100: 327: 25.00
+	Hs
		438022 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		LIMK1_HUMAN (62-312): 5.56e-66: 228: 44.40
+	Hs
		431683 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		LIMK1_HUMAN (62-312): 5.56e-66: 228: 44.40
+	Hs
		438023 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		LIMK2_HUMAN (62-318): 8.84e-61: 214: 40.86
+	Hs
		431684 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		LIMK2_HUMAN (62-318): 8.84e-61: 214: 40.86
+	Hs
		538167 ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54		LIMK2_HUMAN (62-318): 8.84e-61: 214: 40.86
+	Hs
		863776 H90B4_HUMAN (25-328): 1.55e-133: 392: 83.22		LIMK1_HUMAN (62-312): 5.56e-66: 228: 44.40
+	Hs
		863830 H90B4_HUMAN (25-328): 1.55e-133: 392: 83.22		LIMK2_HUMAN (62-318): 8.84e-61: 214: 40.86
+	Zm
		8229 A0A1D6LMW9_MAIZE (5-348): 2.19e-139: 416: 50.43		A0A1D6ELX5_MAIZE (62-316): 9.8e-32: 132: 35.36
+	At
		287794 HS905_ARATH (1-342): 1.84e-138: 413: 45.58		O82754_ARATH (62-324): 1.36e-29: 125: 34.78