HitPredict

Interactor 1: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Interactor 2: TRI56 (Q9BRZ2)
E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56)
Gene: TRIM56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 351 Hs			1 755
+	Hs
		438479 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRI56_HUMAN (1-755): 7.12e-171: 511: 100.00
+	Hs
		432214 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRI56_HUMAN (1-755): 7.12e-171: 511: 100.00
+	Hs
		438503 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRIM2_HUMAN (1-749): 9.85e-157: 475: 18.48
+	Hs
		432239 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRIM2_HUMAN (1-749): 9.85e-157: 475: 18.48
+	Hs
		437880 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		RO52_HUMAN (17-526): 8.51e-85: 278: 13.95
+	Hs
		584990 Q6PK50_HUMAN (1-345): 2.04e-180: 505: 100.00		RO52_HUMAN (17-526): 8.51e-85: 278: 13.95
+	Hs
		438502 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRIM6_HUMAN (7-496): 5.41e-67: 231: 10.51
+	Hs
		175632 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRI18_HUMAN (13-399): 5.24e-64: 228: 15.94
+	Hs
		438499 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRIM8_HUMAN (16-509): 2.87e-63: 222: 17.66
+	Hs
		437920 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		PML_HUMAN (3-527): 1.79e-60: 221: 17.28
+	Hs
		438501 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRIM7_HUMAN (1-478): 3.63e-61: 216: 13.14
+	Hs
		432238 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRIM7_HUMAN (1-478): 3.63e-61: 216: 13.14
+	Hs
		438587 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRI10_HUMAN (1-501): 8.66e-60: 211: 13.01
+	Hs
		438549 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRI36_HUMAN (1-351): 3.21e-55: 204: 15.00
+	Hs
		431597 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRI23_HUMAN (19-339): 8e-49: 183: 20.34
+	Hs
		438120 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TRI32_HUMAN (620-750): 1.42e-12: 73.2: 18.62
+	Hs
		431794 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		TRI32_HUMAN (620-750): 1.42e-12: 73.2: 18.62
+	Hs
		438286 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		NHLC1_HUMAN (1-135): 5.96e-10: 64: 17.88
+	Hs
		1162502 Q6PK50_HUMAN (1-345): 2.04e-180: 505: 100.00		NHLC1_HUMAN (1-135): 5.96e-10: 64: 17.88
+	Hs
		431976 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		NHLC1_HUMAN (1-135): 5.96e-10: 64: 17.88