HitPredict

Interactor 1: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Interactor 2: WSB2 (Q9NYS7)
WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)
Gene: WSB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 404
+	Hs
		438571 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		WSB2_HUMAN (1-404): 1.2e-94: 291: 100.00
+	Hs
		432310 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		WSB2_HUMAN (1-404): 1.2e-94: 291: 100.00
+	Hs
		538425 ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54		WSB2_HUMAN (1-404): 1.2e-94: 291: 100.00
+	Hs
		438048 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		WDR5_HUMAN (281-403): 2.3e-31: 123: 14.06
+	Hs
		437971 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		LIS1_HUMAN (329-404): 6.29e-15: 77.8: 13.58
+	Hs
		431630 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		LIS1_HUMAN (329-404): 6.29e-15: 77.8: 13.58
+	Sc
		365738 HSP82_YEAST (11-350): 7.63e-148: 435: 66.86		TUP1_YEAST (3-185): 2.77e-30: 124: 16.75
+	Cr
		65491 A8J1U1_CHLRE (9-349): 1.63e-165: 480: 66.37		MUT11_CHLRE (126-276): 1.61e-12: 70.1: 28.29
+	Sc
		366669 HSP82_YEAST (11-350): 7.63e-148: 435: 66.86		COPA_YEAST (229-401): 1.47e-25: 111: 13.48
+	Sc
		365880 HSP82_YEAST (11-350): 7.63e-148: 435: 66.86		PWP2_YEAST (2-291): 7.6e-24: 105: 9.04
+	Hs
		538184 ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54		WDR5_HUMAN (281-403): 2.3e-31: 123: 14.06
+	Ca
		483034 HSP90_CANAL (9-350): 9.16e-144: 424: 64.14		TUP1_CANAL (292-403): 3.12e-23: 103: 16.79
+	Sc
		366167 HSP82_YEAST (11-350): 7.63e-148: 435: 66.86		TAF5_YEAST (123-360): 7.3e-18: 87.8: 25.77
+	Sc
		543602 HSC82_YEAST (13-350): 9.86e-147: 432: 65.19		TAF5_YEAST (123-360): 7.3e-18: 87.8: 25.77
+	Hs
		538141 ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54		LIS1_HUMAN (329-404): 6.29e-15: 77.8: 13.58