HitPredict

Interactor 1: TRAF7 (Q6Q0C0)
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.-) (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)
Gene: TRAF7

Interactor 2: NELL2 (Q99435)
Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2)
Gene: NELL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 670 Hs			1 816
+	Hs
		126390 TRAF7_HUMAN (1-670): 1.55e-180: 530: 100.00		MATN2_HUMAN (486-795): 1.72e-24: 112: 21.02
+	Hs
		1253294 POC1B_HUMAN (507-669): 1.96e-36: 144: 17.06		NELL2_HUMAN (1-816): 4.02e-126: 399: 100.00
+	Hs
		980485 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		NOTC2_HUMAN (400-815): 1.5e-25: 116: 19.96
+	Hs
		804311 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		NOTC1_HUMAN (167-649): 2.93e-21: 102: 13.36
+	Dm
		484996 EBI_DROME (212-548): 3.2e-50: 188: 14.53		CRB_DROME (635-814): 2.66e-10: 66.5: 13.72
+	Hs
		944124 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		JAG1_HUMAN (158-493): 3.44e-10: 66.1: 8.55
+	Ce
		537588 SEL10_CAEEL (380-495): 3.39e-16: 84.1: 20.49		LIN12_CAEEL (451-805): 4.65e-29: 127: 20.59
+	Hs
		434633 WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21		TSP1_HUMAN (199-741): 5.64e-09: 61.9: 11.05