HitPredict

Interactor 1: RICTR (Q6QI06)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)
Gene: Rictor

Interactor 2: LST8 (Q9DCJ1)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: Mlst8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

The method score is based on:

Property	Details
Experiments	27340174, 36927703, 22307628, 18925875, 18505677
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007010 - cytoskeleton organization GO:0030307 - positive regulation of cell growth GO:0030838 - positive regulation of actin filament polymerization GO:0031669 - cellular response to nutrient levels GO:0031932 - TORC2 complex and 4 others more... GO:0032008 - positive regulation of TOR signaling GO:0043066 - negative regulation of apoptotic process GO:0043539 - protein serine/threonine kinase activator activity GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	1708
Mm

1	326

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024