HitPredict

Interactor 1: M9PI41 (M9PI41)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: sti

Interactor 2: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22084308
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0005737 - cytoplasm GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1858 Dm			1 192
+	Hs
		925229 DMPK_HUMAN (85-578): 1.04e-119: 394: 32.74		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		623871 KPCL_HUMAN (78-441): 3.75e-109: 366: 31.22		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11
+	Hs
		254468 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		254464 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53
+	Hs
		254472 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21
+	Hs
		254433 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RHOC_HUMAN (1-192): 5.91e-76: 227: 85.49
+	Hs
		254462 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RAC3_HUMAN (1-179): 7e-75: 225: 57.54
+	Hs
		254467 ROCK2_HUMAN (792-1417): 6.6e-35: 148: 12.18		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11
+	Hs
		925766 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		901094 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53
+	Hs
		148653 CTRO_HUMAN (1052-1532): 5.99e-25: 116: 9.90		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		951494 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21
+	Hs
		545725 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16
+	Hs
		894628 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89
+	Hs
		148608 CTRO_HUMAN (1052-1532): 5.99e-25: 116: 9.90		RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53
+	Hs
		892702 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RAC3_HUMAN (1-179): 7e-75: 225: 57.54
+	Dm
		776947 GEK_DROME (682-1098): 3.61e-27: 123: 14.15		CDC42_DROME (1-192): 2.6e-74: 223: 51.30
+	Hs
		916101 MRCKB_HUMAN (997-1518): 2.71e-27: 123: 11.28		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11
+	Hs
		148297 CTRO_HUMAN (1052-1532): 5.99e-25: 116: 9.90		RHOC_HUMAN (1-192): 5.91e-76: 227: 85.49
+	Hs
		148632 CTRO_HUMAN (1052-1532): 5.99e-25: 116: 9.90		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11