Interactor 1: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Interactor 2: SIN1 (Q9BPZ7)
Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) (mSIN1)
Gene: MAPKAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 18566586, 17043309, 16962653, 33378666, 29567957, 17461779, 20832730, 21045808, 21177249, 19875983, 18030348, 18570873, 21343617, 22084251, 31665642, 22307628, 35271311, 35973513, 37120454, 18566587 and 6 others

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Identification Methods affinity chromatography technology, pull down, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, protein kinase assay, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0007010 - cytoskeleton organization
GO:0019901 - protein kinase binding
GO:0030307 - positive regulation of cell growth
and 5 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1708
Hs

1 522
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024