HitPredict

Interactor 1: SAMD1 (Q6SPF0)
Sterile alpha motif domain-containing protein 1 (SAM domain-containing protein 1) (Atherin)
Gene: SAMD1

Interactor 2: LMBL3 (Q96JM7)
Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1)
Gene: L3MBTL3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.936

Property	Details
Experiments	26496610, 28514442, 27705803, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SAM_1~SAM_1
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0090308 - regulation of DNA methylation-dependent heterochromatin formation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 780
+	Hs
		1139330 SAM13_HUMAN (455-531): 4.64e-34: 126: 67.53		LMBL3_HUMAN (1-780): 0: 1015: 100.00
+	Hs
		1139329 SAM13_HUMAN (455-531): 4.64e-34: 126: 67.53		LMBL4_HUMAN (184-774): 0: 695: 51.32
+	Hs
		1282127 CHAP1_HUMAN (1-376): 2.41e-10: 65.2: 12.20		LMBL2_HUMAN (92-550): 9.3e-71: 247: 23.38
+	Hs
		1164476 SAMD1_HUMAN (1-538): 1.87e-41: 158: 100.00		SMBT1_HUMAN (330-713): 2.36e-32: 136: 19.90
+	Hs
		1138552 SAMD1_HUMAN (1-538): 1.87e-41: 158: 100.00		SMBT2_HUMAN (621-772): 5e-30: 129: 22.44
+	Hs
		1164452 SAMD1_HUMAN (1-538): 1.87e-41: 158: 100.00		SCMH1_HUMAN (556-773): 8.82e-28: 121: 15.91
+	Hs
		1139331 SAM13_HUMAN (455-531): 4.64e-34: 126: 67.53		SMBT1_HUMAN (330-713): 2.36e-32: 136: 19.90
+	Hs
		1139328 SAMD1_HUMAN (1-538): 1.87e-41: 158: 100.00		SAM13_HUMAN (701-776): 2.07e-25: 103: 32.91