Interactor 1: SARM1 (Q6SZW1)
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)
Gene: SARM1

Interactor 2: SARM1 (Q6SZW1)
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)
Gene: SARM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 31439792
Identification Methods x-ray crystallography, x ray scattering, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SAM_2~SAM_2, TIR_2~TIR_2
Common GO terms GO:0003953 - NAD+ nucleosidase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
and 21 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 724
Hs

1 724
+ Mm
+ Ce
+ Sc
+ Sp
+ Sp
+ Sc
+ At
+ Mm

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Last updated: 15 Jul 2024