HitPredict

Interactor 1: SARM1 (Q6SZW1)
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)
Gene: SARM1

Interactor 2: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	17258210, 26592460
Identification Methods	protein complementation assay, pull down, mammalian protein protein interaction trap
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	TIR_2~TIR_2
Common GO terms	GO:0045087 - innate immune response
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 235
+	Hs
		1164529 SARM1_HUMAN (1-724): 0: 933: 100.00		TCAM1_HUMAN (71-227): 8.18e-67: 220: 33.13