Interactor 1: SARM1 (Q6SZW1)
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)
Gene: SARM1

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 17258210, 26592460
Identification Methods protein complementation assay, pull down, mammalian protein protein interaction trap
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TIR_2~TIR_2
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0009986 - cell surface
GO:0032991 - protein-containing complex
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 724
Hs

1 296
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024