HitPredict

Interactor 1: NHS (Q6T4R5)
Actin remodeling regulator NHS (Congenital cataracts and dental anomalies protein) (Nance-Horan syndrome protein)
Gene: NHS

Interactor 2: NHSL3 (Q9P206)
NHS-like protein 3
Gene: NHSL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030154 - cell differentiation
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1651 Hs			1 1035
+	Hs
		1132223 NHSL1_HUMAN (186-1650): 2.62e-29: 130: 16.92		NHSL3_HUMAN (1-1035): 9.42e-93: 320: 100.00
+	Hs
		1303336 MUC4_HUMAN (294-1650): 6.2e-50: 198: 10.34		MUC4_HUMAN (87-1032): 5.54e-37: 154: 11.64
+	Hs
		554259 MUC1_HUMAN (9-990): 2.46e-31: 136: 9.62		MUC1_HUMAN (176-1033): 2.85e-50: 195: 15.55
+	Hs
		869494 KMT2C_HUMAN (952-1625): 5.15e-36: 152: 13.88		ATN1_HUMAN (61-1032): 4.58e-11: 69.3: 10.60
+	Hs
		152667 KMT2C_HUMAN (952-1625): 5.15e-36: 152: 13.88		KMT2D_HUMAN (468-1035): 2.27e-10: 67.3: 14.56
+	Hs
		1056827 MDC1_HUMAN (55-1196): 1.34e-24: 114: 10.45		MDC1_HUMAN (287-1032): 1.49e-17: 90.8: 12.39
+	Mm
		1351630 PCLO_MOUSE (4-1542): 2.54e-12: 74.6: 8.94		PCLO_MOUSE (18-1033): 6.22e-29: 128: 9.36
+	Hs
		1056876 MDC1_HUMAN (55-1196): 1.34e-24: 114: 10.45		MICA3_HUMAN (375-970): 4.02e-09: 63.3: 16.53
+	Hs
		577685 CIC_HUMAN (32-1650): 2.13e-17: 91.1: 9.06		SON_HUMAN (486-996): 5.04e-14: 79.2: 17.93
+	Dm
		1214590 Q9VLS7_DROME (3-947): 4.87e-16: 86.9: 9.42		Q8IQA6_DROME (91-972): 1.73e-14: 80.9: 10.69
+	Dm
		113976 M9PB30_DROME (18-889): 2.92e-10: 67.8: 10.16		M9PB30_DROME (25-637): 6.76e-16: 85.5: 9.98
+	Hs
		1329244 TARA_HUMAN (508-1582): 7.21e-09: 63.3: 13.43		TARA_HUMAN (96-1030): 1.39e-16: 87.7: 9.83