Interactor 1: MIC60 (Q16891)
MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89)
Gene: IMMT

Interactor 2: SAM50 (Q9Y512)
Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3)
Gene: SAMM50

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.689

The method score is based on:

Property Details
Experiments 32877691, 34037656, 27153535, 17624330
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001401 - SAM complex
GO:0005739 - mitochondrion
GO:0007007 - inner mitochondrial membrane organization
GO:0016020 - membrane
GO:0042407 - cristae formation
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 758
Hs

1 469
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025