HitPredict

Interactor 1: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 147
+	Hs
		849345 LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919756 LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895817 LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		851826 LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		896468 LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Zm
		21257 A0A1D6HSI7_MAIZE (3-306): 3.53e-52: 197: 15.81		A0A1D6LKH6_MAIZE (2-144): 1.45e-70: 211: 46.15