HitPredict

Interactor 1: ARSK (Q6UWY0)
Arylsulfatase K (ASK) (EC 3.1.6.1) (Glucuronate-2-sulfatase) (EC 3.1.6.18) (Telethon sulfatase)
Gene: ARSK

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	32409323, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 293
+	Hs
		1165674 ARSK_HUMAN (1-536): 0: 636: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1219531 SULF2_HUMAN (4-440): 5.41e-112: 354: 21.43		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		549103 GNS_HUMAN (27-473): 1.72e-109: 339: 19.72		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		849848 SPHM_HUMAN (8-469): 1.55e-85: 275: 21.90		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1219541 SULF2_HUMAN (4-440): 5.41e-112: 354: 21.43		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1219555 SULF1_HUMAN (4-424): 2.2e-109: 347: 20.85		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		550480 ARSB_HUMAN (20-476): 4.3e-113: 347: 16.21		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		549108 GNS_HUMAN (27-473): 1.72e-109: 339: 19.72		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		99729 F5H4C6_HUMAN (67-310): 1.05e-51: 178: 15.79		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		849851 SPHM_HUMAN (8-469): 1.55e-85: 275: 21.90		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17