HitPredict

Interactor 1: CXL17 (Q6UXB2)
C-X-C motif chemokine 17 (6-Cys CXCL17) (Dendritic cell and monocyte chemokine-like protein) (DMC) (VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17]
Gene: CXCL17

Interactor 2: CCL26 (Q9Y258)
C-C motif chemokine 26 (CC chemokine IMAC) (Eotaxin-3) (Macrophage inflammatory protein 4-alpha) (MIP-4-alpha) (Small-inducible cytokine A26) (Thymic stroma chemokine-1) (TSC-1)
Gene: CCL26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 119 Hs			1 94
+	Hs
		1166407 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL13_HUMAN (2-91): 2.05e-31: 107: 33.70
+	Hs
		945620 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL8_HUMAN (16-90): 1.05e-28: 100: 34.21
+	Hs
		1166406 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL17_HUMAN (1-89): 5.64e-28: 98.9: 29.21
+	Hs
		528221 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL2_HUMAN (16-93): 9.59e-27: 95.8: 27.85
+	Hs
		528267 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL5_HUMAN (14-90): 3.98e-25: 91.6: 37.66
+	Hs
		179467 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL25_HUMAN (4-94): 5.9e-24: 90: 27.84
+	Hs
		1166409 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		XCL2_HUMAN (6-92): 2.14e-21: 82.7: 28.74
+	Hs
		944668 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL20_HUMAN (1-93): 2.02e-21: 82.3: 25.26
+	Hs
		815515 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		XCL1_HUMAN (6-92): 5.59e-21: 81.5: 29.89
+	Hs
		134308 CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00		CCL21_HUMAN (25-91): 5.26e-17: 71.9: 28.17