Interactor 1: CASPC (Q6UXS9)
Inactive caspase-12 (CASP-12)
Gene: CASP12

Interactor 2: CASPC (Q6UXS9)
Inactive caspase-12 (CASP-12)
Gene: CASP12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 12097332, 11278723
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, Peptidase_C14~Peptidase_C14
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0006508 - proteolysis
GO:0043525 - positive regulation of neuron apoptotic process
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 341
Hs

1 341
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Last updated: 15 Jul 2024