Interactor 1: UBXN8 (O00124)
UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6)
Gene: UBXN8

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 25078495, 29997244, 35271311, 21949850, 26389662, 18775313
Identification Methods two hybrid, fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_2~UBX, CDC48_N~UBX
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0036503 - ERAD pathway
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 270
Hs

1 806
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Ce
+ Hs
+ Mm
+ Sp
+ Sc
+ Sc
+ Ce
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024