Interactor 1: DLK2 (Q6UY11)
Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9)
Gene: DLK2

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, EGF~EGF_CA
Common GO terms GO:0005112 - Notch binding
GO:0005509 - calcium ion binding
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 383
Hs

1 2321
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Last updated: 15 Jul 2024