HitPredict

Interactor 1: BCOR (Q6W2J9)
BCL-6 corepressor (BCoR)
Gene: BCOR

Interactor 2: NACC1 (Q96RE7)
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)
Gene: NACC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19121354
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042826 - histone deacetylase binding GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1755 Hs			1 527
+	Hs
		312071 BCOR_HUMAN (1-1755): 0: 2385: 100.00		ZBT7A_HUMAN (1-431): 6.26e-61: 212: 16.86
+	Hs
		166172 BCOR_HUMAN (1-1755): 0: 2385: 100.00		ZBTB5_HUMAN (7-332): 3.13e-50: 184: 18.73
+	Hs
		781386 BCOR_HUMAN (1-1755): 0: 2385: 100.00		BCL6_HUMAN (6-350): 2.1e-49: 182: 19.07
+	Mm
		781504 BCOR_MOUSE (1-1755): 0: 2352: 88.59		BCL6_MOUSE (6-350): 1.92e-52: 191: 19.35
+	Mm
		1208441 BCOR_MOUSE (1-1755): 0: 2352: 88.59		ZBT7C_MOUSE (3-116): 8.32e-13: 72.8: 37.60
+	Hs
		1285481 OSBL1_HUMAN (1458-1633): 2.4e-35: 149: 29.63		NACC2_HUMAN (1-486): 2.41e-132: 398: 53.75
+	Hs
		1200814 EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87		ZBT46_HUMAN (3-398): 2.02e-61: 213: 21.34
+	Hs
		862134 DAPK1_HUMAN (1456-1753): 6.93e-54: 210: 12.18		KLH20_HUMAN (4-267): 7.84e-69: 234: 17.47
+	Dm
		570922 Q3KN55_DROME (1238-1734): 1.03e-71: 257: 10.78		TTKB_DROME (2-307): 2.06e-45: 170: 16.99
+	Hs
		781451 EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87		BCL6_HUMAN (6-350): 2.1e-49: 182: 19.07
+	Mm
		1145273 ANR17_MOUSE (1289-1753): 6.54e-67: 253: 13.21		ZBT7B_MOUSE (2-354): 9.29e-45: 167: 18.98
+	Mm
		1125429 EHMT1_MOUSE (1226-1635): 8.01e-66: 248: 15.31		ZBT7B_MOUSE (2-354): 9.29e-45: 167: 18.98
+	Dm
		65551 A8JNM5_DROME (1159-1750): 2.9e-65: 248: 13.65		TTKA_DROME (2-354): 8.8e-43: 165: 15.17
+	Hs
		276180 PSD10_HUMAN (1471-1658): 1.13e-40: 152: 20.64		KEAP1_HUMAN (3-260): 7.39e-59: 207: 14.66
+	Hs
		781443 OSBL1_HUMAN (1458-1633): 2.4e-35: 149: 29.63		BCL6_HUMAN (6-350): 2.1e-49: 182: 19.07
+	Hs
		1326718 ANKR2_HUMAN (1465-1571): 1.57e-35: 141: 34.58		ZBTB3_HUMAN (7-304): 5.36e-47: 174: 19.88
+	Hs
		1235654 EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87		ZBTB2_HUMAN (7-117): 8.4e-11: 66.2: 34.82
+	Hs
		1206021 MIB1_HUMAN (1313-1647): 8.4e-44: 176: 14.75		ZBT10_HUMAN (16-141): 6e-12: 70.5: 33.58