HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 970
+	Hs
		724884 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		725013 TARA_HUMAN (231-985): 1.44e-51: 201: 35.57		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		724876 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		724963 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		148466 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH11_HUMAN (2-965): 0: 1001: 26.34
+	Hs
		148461 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		148460 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		725086 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		1033099 SLK_HUMAN (178-999): 9.15e-17: 87.8: 10.02		MYO7A_HUMAN (1-959): 0: 1029: 26.50
+	Hs
		725065 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		522585 MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36		MYH7_HUMAN (2-934): 0: 1000: 26.13
+	Hs
		724687 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		724686 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		725095 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Dm
		1303383 MYSN_DROME (457-975): 1.82e-17: 90.5: 15.79		MYO7A_DROME (9-950): 0: 990: 27.25
+	Hs
		522657 MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36		MYH4_HUMAN (12-802): 0: 985: 31.16
+	Hs
		1153448 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		149417 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		725068 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01