HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 315
+	Hs
		1167395 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		793015 DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		148168 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		148190 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		1153322 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		903302 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		149156 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		148610 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		724952 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		725215 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1068625 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1189782 MYH14_HUMAN (595-972): 3.69e-09: 63.1: 14.89		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		903240 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		148858 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		TAF5_HUMAN (12-219): 1.62e-21: 97.1: 32.08
+	Hs
		1240465 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		POC1A_HUMAN (3-95): 2.11e-21: 95.4: 29.03
+	Hs
		255308 HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		903334 MYH14_HUMAN (595-972): 3.69e-09: 63.1: 14.89		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		728492 MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57		POC1A_HUMAN (3-95): 2.11e-21: 95.4: 29.03