HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~RhoGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1025 Hs			1 914
+	Hs
		1333814 CE164_HUMAN (163-980): 5.02e-36: 150: 11.93		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		149299 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725023 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725246 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		728517 MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1068667 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		167092 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		ARHGB_HUMAN (453-651): 2.54e-12: 73.2: 23.53
+	Hs
		1273280 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		149142 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		50598 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		200789 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		ARHG9_HUMAN (404-798): 2.6e-76: 260: 19.36
+	Hs
		724913 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		254475 ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81		AKP13_HUMAN (274-912): 7.43e-83: 295: 13.83
+	Hs
		50564 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		1068638 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53
+	Hs
		1068677 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		ARHG4_HUMAN (350-880): 1.39e-79: 274: 17.20
+	Hs
		724971 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		548710 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82
+	Hs
		1068630 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		Q96D37_HUMAN (390-707): 1.05e-76: 268: 21.82
+	Hs
		962561 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93