HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: CENPJ (Q9HC77)
Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CENPJ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 1338
+	Hs
		1167392 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		1268090 TARA_HUMAN (231-985): 1.44e-51: 201: 35.57		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		1153312 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		149126 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		724943 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		724884 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		725013 TARA_HUMAN (231-985): 1.44e-51: 201: 35.57		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		148461 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH10_HUMAN (401-1280): 4.97e-27: 122: 9.17
+	Hs
		148466 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH11_HUMAN (562-1205): 5.03e-23: 109: 7.90
+	Hs
		724876 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		551742 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		DESP_HUMAN (653-1103): 3.01e-09: 64.2: 15.30
+	Hs
		148460 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		148359 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		DESP_HUMAN (653-1103): 3.01e-09: 64.2: 15.30
+	Hs
		724687 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYH10_HUMAN (401-1280): 4.97e-27: 122: 9.17
+	Hs
		522657 MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36		MYH4_HUMAN (70-935): 6.8e-27: 122: 7.61
+	Hs
		725095 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		MYH10_HUMAN (401-1280): 4.97e-27: 122: 9.17
+	Hs
		522585 MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36		MYH7_HUMAN (431-1261): 4.84e-26: 119: 8.67
+	Hs
		724686 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Dm
		1303379 MYSN_DROME (457-975): 1.82e-17: 90.5: 15.79		MYSN_DROME (332-1038): 7.07e-12: 72.6: 15.53