HitPredict

Interactor 1: KIF2A (O00139)
Kinesin-like protein KIF2A (Kinesin-2) (hK2)
Gene: KIF2A

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 706 Hs			1 758
+	Hs
		116777 KIF2A_HUMAN (1-706): 0: 767: 100.00		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		654043 KIF2C_HUMAN (1-702): 0: 641: 52.11		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		497871 KIF3A_HUMAN (215-701): 5.7e-155: 466: 27.61		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496927 KIF1A_HUMAN (223-703): 4.83e-143: 459: 27.10		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		216897 KIF1C_HUMAN (223-688): 2.25e-145: 454: 27.24		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		166357 KIF3B_HUMAN (215-700): 1.31e-143: 439: 27.43		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		653940 KIF11_HUMAN (223-704): 7.46e-147: 456: 29.82		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		91550 KIF11_HUMAN (223-704): 7.46e-147: 456: 29.82		E7EVA0_HUMAN (217-742): 5.43e-26: 117: 24.87
+	Ce
		109403 UN104_CAEEL (222-657): 5.21e-141: 452: 28.08		H2KY94_CAEEL (465-688): 3.39e-25: 107: 33.48