Interactor 1: NBN (Q6XV80)
Nibrin (Nijmegen breakage syndrome protein 1 homolog) (xNBS1)
Gene: nbn.L

Interactor 2: TOB1A (Q800K6)
DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP)
Gene: topbp1-A

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 19279141, 27590578, 22391207
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT~BRCT, BRCT~PTCB-BRCT
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
GO:0035861 - site of double-strand break
GO:0043539 - protein serine/threonine kinase activator activity
GO:0140031 - phosphorylation-dependent protein binding
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 763
Xl

1 1513
+ Hs
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+ Dm
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024