HitPredict

Interactor 1: DNMBP (Q6XZF7)
Dynamin-binding protein (Scaffold protein Tuba)
Gene: DNMBP

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~SH3_1, SH3_1~SH3_2, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_2~SH3_2, SH3_2~SH3_9
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1577 Hs			1 1190
+	Hs
		990871 DNMBP_HUMAN (1-1577): 0: 917: 100.00		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		1333783 ECT2_HUMAN (553-1252): 2.19e-77: 279: 14.03		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		506670 BCR_HUMAN (338-1033): 1.2e-68: 256: 17.12		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		1126376 SH319_HUMAN (3-127): 1.19e-14: 81.4: 24.62		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		990936 ECT2_HUMAN (553-1252): 2.19e-77: 279: 14.03		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		159251 ARHGQ_HUMAN (395-1166): 3.84e-66: 244: 14.82		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Ce
		284011 O76572_CAEEL (629-1093): 8.62e-67: 241: 18.09		Q20398_CAEEL (28-892): 4.39e-90: 316: 17.64
+	Hs
		279898 TRIO_HUMAN (772-1497): 4.83e-62: 237: 14.67		PALS2_HUMAN (423-890): 8.19e-96: 318: 15.77
+	Hs
		159201 TIAM1_HUMAN (722-972): 1.46e-59: 228: 25.74		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Hs
		990858 SH319_HUMAN (3-127): 1.19e-14: 81.4: 24.62		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Mm
		88351 D3YYY8_MOUSE (395-1166): 9.41e-79: 282: 15.73		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		57852 KALRN_MOUSE (771-1497): 3.04e-71: 267: 15.08		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		57873 KALRN_MOUSE (771-1497): 3.04e-71: 267: 15.08		DLG2_MOUSE (8-534): 5.21e-45: 178: 15.58
+	Hs
		1021546 ARHGQ_HUMAN (395-1166): 3.84e-66: 244: 14.82		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		942336 TIAM1_HUMAN (722-972): 1.46e-59: 228: 25.74		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Hs
		1021484 TIAM1_HUMAN (722-972): 1.46e-59: 228: 25.74		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Dm
		954558 SIF2_DROME (759-969): 1e-14: 82.4: 27.92		CSKP_DROME (441-888): 1.42e-95: 328: 17.33
+	Hs
		1271019 ARHGQ_HUMAN (395-1166): 3.84e-66: 244: 14.82		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Mm
		1143413 SH3R3_MOUSE (48-298): 3.79e-16: 86.7: 16.47		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143451 SH3K1_MOUSE (158-298): 4.21e-12: 73.2: 30.26		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89