Interactor 1: HACD2 (Q6Y1H2)
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B)
Gene: HACD2

Interactor 2: TECR (Q9NZ01)
Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)
Gene: TECR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 25416956, 32296183, 30021884, 34349018, unassigned1304
Identification Methods two hybrid, proximity labelling technology, cross-linking study, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030497 - fatty acid elongation
GO:0035338 - long-chain fatty-acyl-CoA biosynthetic process
GO:0042761 - very long-chain fatty acid biosynthetic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 254
Hs

1 308
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024