HitPredict

Interactor 1: KIF2A (O00139)
Kinesin-like protein KIF2A (Kinesin-2) (hK2)
Gene: KIF2A

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Kinesin~Tubulin, Kinesin~Tubulin_C
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0051301 - cell division
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 706 Hs			1 451
+	Hs
		116856 KIF2A_HUMAN (1-706): 0: 767: 100.00		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		116813 KIF2A_HUMAN (1-706): 0: 767: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		90009 D6R9M0_HUMAN (1-489): 0: 554: 100.00		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		231494 KIF1B_HUMAN (223-706): 6.34e-145: 466: 26.68		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Dm
		415591 KLP68_DROME (210-701): 3.34e-148: 452: 28.82		TBA1_DROME (1-439): 0: 713: 97.49
+	Dm
		415619 Q9VRK9_DROME (209-701): 1.93e-148: 449: 28.41		TBA1_DROME (1-439): 0: 713: 97.49
+	Hs
		309316 KIF4A_HUMAN (271-557): 1.14e-43: 171: 37.46		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		309298 KIF4A_HUMAN (271-557): 1.14e-43: 171: 37.46		TBB4B_HUMAN (1-437): 0: 697: 40.96