HitPredict

Interactor 1: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1374 Hs			1 480
+	Hs
		681496 LMTK1_HUMAN (1-1374): 0: 976: 100.00		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		609471 FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		508145 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Mm
		1142038 MUSK_MOUSE (20-402): 8.64e-113: 377: 26.47		DNJA3_MOUSE (1-480): 0: 555: 87.50
+	Hs
		1081563 NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		412302 FYN_HUMAN (104-408): 1.36e-104: 344: 30.07		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Dm
		448256 INSR_DROME (24-883): 2.43e-128: 441: 17.09		Q9VFV9_DROME (89-469): 4.7e-111: 335: 23.19
+	Hs
		507875 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243277 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		681463 NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243425 NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		411469 INSR_HUMAN (111-395): 4.12e-41: 167: 36.27		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		411615 LCK_HUMAN (98-410): 1.51e-107: 352: 24.20		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243255 LCK_HUMAN (98-410): 1.51e-107: 352: 24.20		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		435729 IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		411313 INSR_HUMAN (111-395): 4.12e-41: 167: 36.27		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243254 INSR_HUMAN (111-395): 4.12e-41: 167: 36.27		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		435551 IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243262 IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243251 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38